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SIRT1 Protects Dendrites, Mitochondria and Synapses from Aβ Oligomers in Hippocampal Neurons
Aging is a major risk factor in the onset of neurodegenerative diseases, such as Alzheimer’s disease (AD). SIRT1, a β-NAD+-dependent histone deacetylase activity, holds great potential for promoting longevity, preventing against disease and increasing cell survival. We report here, that SIRT1 protects against the damage caused by Aβ... Read More»
Juan A Godoy, Claudio Allard, Macarena S Arrázola, Juan M Zolezzi and Nibaldo C Inestrosa
Research Article: J Alzheimers Dis Parkinsonism 2013, 3:126
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