91桃色

ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
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  • J Gastro intest DigSyst,
  • DOI: 10.4172/2161-069X.1000650

Anticholinesterase Activities: The Possible Mechanism Suggestive Of Therapeutic Effect of Allicin in Garlic on Intestinal Neuronal Dysplasia Type B

Kehinde Alare*, Busayo Adetunji and Taiwo Alare
*Corresponding Author : Kehinde Alare, Department of Medicine, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria, Email: kehinde_alare@thismaze.com

Abstract

Allicin components of garlic have been helpful medicinally because of its action as an indirect acting cholinergic agonist through its inhibitory effects on both acetylcholinesterase and butrylcholinesterase. This could also suggest therapeutic effects in the management of intestinal neuronal dysplasia type B, a disease which one of its pathophysiology has linked with increase acetylcholinesterase activities in the gut.

Keywords: Intestinal neuronal dysplasia; Allicin; Anticholinesterase; Chronic constipation; Garlic

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