Short Communication
Carbapenem-Resistant Klebsiella Pneumoniae Osteomyelitis and Soft Tissue Infections: A Descriptive Case Series
| Camila D Odio1, David van Duin2, Eric Cober2,3, Lucileia Teixeira-Johnson2,3, Steven Schmitt2,3 and Jorgelina de Sanctis4* | ||
| 1Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland Clinic Foundation, Cleveland, OH, USA | ||
| 2Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, NC, USA | ||
| 3Department of Infectious Diseases, Cleveland Clinic Foundation, Cleveland, OH, USA | ||
| 4Division of Infectious Disease, Spectrum Health Medical Group, Grand Rapids, MI, USA | ||
| Corresponding Author : | Jorgelina De Sanctis MD, Department of Infectious Diseases Spectrum Health, 230 Michigan Ave, NE Grand Rapids, MI 49503, USA Tel: 616-633-1433 Fax: 616-391 8665 E-mail: Jorgelina.deSanctis@spectrumhealth.org |
|
| Received November 26, 2014; Accepted December 16, 2014; Published January 07, 2015 | ||
| Citation: Odio CD, van Duin D, Cober E, Teixeira-Johnson L, Schmitt S, et al. (2015) Carbapenem-Resistant Klebsiella Pneumoniae Osteomyelitis and Soft Tissue Infections: A Descriptive Case Series. J Infect Dis Ther 3:200. doi: 10.4172/2332-0877.1000200 | ||
| Copyright: © 2015 Odio CD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | ||
Related article at |
||
Abstract
Antimicrobial therapies for Carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections are limited. We examine the presentation of and response to therapy in CR-KP osteomyelitis and soft tissue infections. Tigecycline monotherapy cured mild infections; the addition of amikacin and colistimethate did not increase survival in dire cases. The 45% mortality rate underscores the gravity of these infections.
