Elucidating Cell Signaling Pathways Involved in the Biocompatibility of Biodegradable Polymer Implants
Received Date: Feb 01, 2025 / Published Date: Feb 28, 2025
Abstract
Biodegradable polymer implants have revolutionized the field of regenerative medicine by facilitating tissue regeneration and reducing the risks associated with permanent implants. Understanding the underlying cell signaling pathways that govern the biocompatibility of these materials is essential for optimizing their performance and enhancing patient outcomes. This article reviews the key signaling cascades—such as integrin-mediated signaling, the mitogen-activated protein kinase (MAPK) pathway, and the phosphoinositide 3-kinase (PI3K)-Akt pathway— implicated in the interactions between biodegradable polymers and cells. The modulation of these pathways can significantly influence cellular behaviors, such as adhesion, proliferation, and differentiation, ultimately impacting the biocompatibility of these implants. By elucidating these processes, we can design better biomaterials that promote tissue integration and healing.
Citation: Liaoyuan S (2025) Elucidating Cell Signaling Pathways Involved in the Biocompatibility of Biodegradable Polymer Implants. Biopolymers Res 9: 252. Doi: 10.4172/bsh.1000252
Copyright: 漏 2025 Liaoyuan S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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