Research Article
Greener Synthesis of Nano Hydroxyapatite using Fatty Acids Template for the Application of Tissue Engineering Nano Hydroxyapatite: Fatty Acids Synthesis and Characterizations
Sumathra Murugan and Mariappan Rajan*Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, India
- Corresponding Author:
- Mariappan Rajan
Department of Natural Products Chemistry
School of Chemistry, Madurai Kamaraj University
Madurai - 625021, India
Tel: +919488014084
E-mail: rajanm153@gmail.com
Received Date: July 11, 2017; Accepted Date: August 10, 2017; Published Date: August 15, 2017
Citation: Sumathra M, Mariappan R (2017) Greener Synthesis of Nano Hydroxyapatite using Fatty acids template for the application of Tissue Engineering Nano Hydroxyapatite: Fatty acids Synthesis and Characterizations. J Mol Pharm Org Process Res 5:136. doi: 10.4172/2329-9053.1000136
Copyright: © 2017 Murugan S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Nano-hydroxyapatite (nano-HAp) is significant import as a bio-ceramic material for use in orthopedic applications because of its comparability in size, crystallography and substance creation with human hard tissue. In this present study, the biologically high interest of nano-HAp was synthesized as green template mode approaches using the various fatty acids like linoleic acid, lauric acid, and oleic acid. The influence of the fatty acid for the formations nano- HAp structure and nature of fatty acid during synthesis was investigated. The nano-HAp functionality, crystallinity, and morphology were determined by FTIR, XRD, and SEM techniques, respectively. The biocompatibility of HAp on MG63 cell line was confirmed by in vitro MTT assay method. The in-vitro studies showed better biocompatibility and cell proliferation results on the template assist synthesized nHAP. These results indicate that nHAp form the green methodology could be a promising material for bone tissue engineering.
