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Clinical Pharmacology & Biopharmaceutics
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  • Review Article   
  • Clin Pharmacol Biopharm,

Impact of Gut Microbiota on Drug Metabolism and Pharmacokinetics

Shabnoor Omara*
Department of Pharmacology, Faculty of Health Sciences, South Africa
*Corresponding Author : Shabnoor Omara, Department of Pharmacology, Faculty of Health Sciences, South Africa, Email: shabnooromara22@gmail.com

Received Date: Jul 01, 2024 / Published Date: Jul 30, 2024

Abstract

The human gut microbiota, a complex ecosystem of microorganisms residing in the gastrointestinal tract, plays a pivotal role in drug metabolism and pharmacokinetics. This article explores the multifaceted impact of gut microbiota on drug metabolism processes, including phase I and phase II reactions, and its influence on drug absorption, distribution, and elimination. Understanding these interactions is crucial for advancing personalized medicine and optimizing therapeutic outcomes by leveraging microbiota modulation strategies. This review synthesizes current knowledge and highlights the clinical implications of microbiota-drug interactions

Citation: Shabnoor O (2024) Impact of Gut Microbiota on Drug Metabolism andPharmacokinetics. Clin Pharmacol Biopharm, 13: 474.

Copyright: © 2024 Shabnoor O. This is an open-access article distributed underthe terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.

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