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Precision Nanomedicine: Engineering Nanoscale Biomaterials for Targeted Delivery of CRISPR-Cas9 Gene Editing Tools

Arzlan Shu-Yan^*

Received Date: Nov 05, 2024 / Published Date: Nov 29, 2024

Citation: Shu-Yan A (2024) Precision Nanomedicine: Engineering Nanoscale Biomaterials for Targeted Delivery of CRISPR-Cas9 Gene Editing Tools. J Biotechnol Biomater, 14: 417.

Copyright: © 2024 Shu-Yan A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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The field of nanomedicine has witnessed transformative advancements with the integration of nanoscale biomaterials for precise therapeutic delivery. This review explores the emerging role of engineered nanomaterials in facilitating the targeted delivery of CRISPR-Cas9 gene-editing tools, a breakthrough technology in genome editing. By addressing key challenges such as off-target effects, immune responses, and delivery efficiency, nanoscale systems— including lipid nanoparticles, polymeric carriers, and hybrid nanocomposites—offer unprecedented control over cellular targeting and intracellular trafficking. These innovations hold the potential to revolutionize therapeutic interventions for genetic disorders, cancers, and infectious diseases, providing a pathway toward safer and more effective geneediting applications. Future directions focus on optimizing biocompatibility, improving in vivo targeting specificity, and advancing clinical translation of these precision nanomedicine strategies