Serotonin Syndrome during Switching of Combined Antidepressant Treatment: A Case Report
Received Date: Apr 09, 2018 / Accepted Date: Apr 17, 2018 / Published Date: Apr 24, 2018
Abstract
When the concentration of serotonin is increased in the central nervous system, it can induce serious adverse reactions known as the serotonin syndrome (SS). We report a case of SS which occurred during the switching of combined antidepressant treatment. The symptoms and treatment of this patient are described. Due to the widespread use of serotonergic drugs, the risk of SS appears to be increasing. Clinicians should be aware of the possibility of SS, especially in patients with a history of serotonergic drug intake, particularly large doses, combinations, when therapeutic doses are adjusted, or when switching from one to another, and in those who present with clinical features of SS.
Keywords: Serotonin syndrome; Antidepressants; Serotonin reuptake inhibitors
Citation: Wang H, Xia Q, Long J, Liu C, Qian X, et al. (2018) Serotonin Syndrome during Switching of Combined Antidepressant Treatment: A Case Report. Neurol Clin Therapeut J 2: 105.
Copyright: © 2018 Wang H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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