91桃色

Abstract

This systematic review and meta-analysis aim to examine the relationship between suicide and cognitive decline, focusing on the incidence rates and contributing risk factors. Cognitive decline, often seen in neurodegenerative diseases such as Alzheimer’s and Parkinson’s, has been increasingly linked to an elevated risk of suicidal behavior. However, the mechanisms underlying this association remain complex and multifaceted. By synthesizing data from a wide range of studies, this review explores how cognitive impairments, depression, social isolation, and other mental health conditions interact to increase the risk of suicide in individuals experiencing cognitive decline. Additionally, we investigate demographic factors, such as age, gender, and underlying medical conditions, that influence the incidence of suicide in this population. Our meta-analysis quantifies the strength of these associations and identifies key risk factors that may inform future prevention and intervention strategies. The findings highlight the urgent need for integrated care models that address both cognitive and mental health challenges in older adults, with an emphasis on proactive suicide prevention.