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Paget�??s disease is a chronic metabolic condition characterized by a local imbalance between the resorbing activity of
osteoclasts and the osteogenic activity of osteoblasts which leads to the remodeling of bone tissue with richly vascularized
foci of loose and compact bone. The cause is believed to be either viral or genetic in origin. We present a rare case of a 40-yearold
female diagnosed with Paget�??s disease of the temporal bone and sphenoid sinus, after having been treated for 5 years for
chronic otitis media. The patient presented with a mass anterior to the right ear and severe headache. She had no history of
tinnitus or vertigo but complained about hearing loss. Rinne�??s test was negative and Weber�??s test showed lateralization to the
right side. Otoneurological examination revealed a mild, mixed-type hearing loss to the right side. Cranial nerves including
facial nerve were normal. There were no motor/sensory deficits or signs of cerebellar dysfunction. Radiological examination
(HRCT & MRI) of the cerebral and visceral skull showed a significant osteosclerotic malformation of the right sphenoid and
temporal bone with some evidence of soft tissue in the sphenoid sinus. Biopsies were taken endoscopically and histological
examination led to the diagnosis of Paget�??s disease. It is possible that the chronic inner ear inflammation might have played
a role in the development of temporal bone Paget�??s disease in this patient. Although temporal bone Paget�??s disease is very
rare it can appear early with symptoms of otitis media and ENTs should include it in the differential diagnosis of patients
unresponsive to treatment.
Biography
Petros Vrettakos is a resident of Otorhinolaryngology at the General Hospital of Nikaia-Piraeus �??Agios Panteleimon�?� (Athens, Greece). He is a PhD candidate and
conducts a clinical and anatomical research on the innervation of trapezius muscle and levator scapulae muscle by the cervical nerve plexus. He has presented
several researches in both Greek and international conferences.
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