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Antimicrobial activity of phenolic extract and essential oil of Ceratonia siliqua L (Caroub): Effect on digestive flora of malnourished children
Joint Event on 13th International Conference on Pediatric Gastroenterology Hepatology & Nutrition & 3rd International Conference on Digestive and Metabolic Diseases
Agro-food and pharmaceutical industries for its richness in oligosaccharides, dietary fiber and polyphenols. These substances
make carob a potential candidate for prebiotic status. The aim of this work is: firstly, to demonstrate the antimicrobial
activity of polyphenol and essential oil of carob at different concentrations against eight strains belonging to the digestive flora
of malnourished children, and secondly, to evaluate the effect of seed extract of Ceratonia siliqua L on the growth of probiotics
and the tested strains of the digestive flora of malnourished children.
Methods: The effect of this plants was investigated through by physico-chemically and microbiological testes,
Results: The results revealed significant antimicrobial activity with an inhibition zone ranging from 5 to 16.5 mm and a
MIC of 3.33% and 8.33% for the phenolic extract; and 5 to 19.6 mm and a MIC of 0.33% for the essential oil. Furthermore,
the confrontation test results show that the two strains (Lactobacillus fermentum and Lactobacillus plantarum) present an
antimicrobial activity against the tested strains. In addition, the inhibitory capacity of L.plantarum and L.fermentum is
improved in the presence of 1% (w / v) of the carob seed extract.
Conclusion: Therefore, this study makes the carob-probiotic association the best candidate for the treatment of diarrhea in
malnourished children.