Journal of Infectious Diseases & Therapy
Open 91桃色
Our Group organises 3000+ Global Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open 91桃色 Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Open 91桃色 Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers
Citations : 1529
Indexed In
- Index Copernicus
- Google Scholar
- Open J Gate
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Publons
- Euro Pub
- ICMJE
Useful Links
Recommended Journals
Related Subjects
Share This Page
GeneXpert: A new tool for the rapid detection of Rifampicin resistance in Mycobacterium tuberculosis
International Conference on Infectious Diseases, Diagnostic Microbiology & Dermatologists Summit on Skin Infections
Muhammad Saeed
Allama Iqbal Medical College, Pakistan
ScientificTracks Abstracts: J Infect Dis Ther
DOI:
Abstract
To evaluate the diagnostic sensitivity and specificity of GeneXpert (MTB/RIF) assay for the detection of rifampicin (RIF) resistance in Mycobacterium tuberculosis (MTB) by comparing the results with conventional drug susceptibility testing (DST) as 芒�?�?Gold Standard芒�?聺. A total of 2200 pulmonary and extra-pulmonary specimens were collected from TB suspects from 2012 to 2014. All specimens were processed for ZN staining, LJ culture according to WHO protocol GeneXpert (MTB/RIF) as per manufacturer instructions. All cases positive for MTB were further processed for DST for RIF. Out of 2200 Tb suspects, 840 (38.18%) cases were GeneXpert (MTB/RIF) positive for MTB. Among these 15.6% (134/840) cases showed RIF resistance. The sensitivity, specificity, PPV and NPV of GeneXpert for RIF resistance were found to be 98.3%. 99.1%, 94.7% and 99.4% respectively by comparing the results with DST. Our study revealed that GeneXpert (MTB/RIF) is an extremely helpful diagnostic tool for detection of RIF resistance in TB suspects with fairly high sensitivity and specificity along with 2 hours turnout time, which facilitates proper in time management and treatment among MDR-TB patients in developing countries.Biography
Muhammad Saeed has completed his BSc in Medical Laboratory Technology from University of Health Sciences Lahore, Pakistan. He is working as a Medical Laboratory Technologist in Punjab Institute of Cardiology Lahore. He has published more than 9 research papers in well reputed Pakistani journal.
Email: twanagol@yahoo.com
