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Recording of accurate medication history and food diet plan is an important part of initial patient assessment after admission in
hospital. Pharmacist has been shown to obtain more accurate medication related information from patient than physician. In
developed countries, pharmacist conducted medication histories which have been reported to save million dollars per hospital per
year and reduction in mortality rate. Unfortunately, in least developed countries, especially in Pakistan, the role of the Physician is
dominant. In Pakistan, Physicians have a limited knowledge of diet, food-food interaction and drug-drug interaction and override
the role of pharmacist. During late January 2012, medicines given by Physicians at the Punjab Institute of Cardiology (PIC) hospital
in the Lahore region of Punjab, Pakistan, claimed the lives of over 100 heart patients. Lack of interest in non-cooperating pharmacists
in recording patient medication history and counseling of patient in determining drug-drug and food-food interaction and lack of
Pharmaceutical Regulations has resulted in such a huge loss. The main aim of the paper is to draw a comparison of existing regulations
and pharmacist�s role for patient safety in Pakistan with that of international standards. Moreover, a road map will be suggested for
implementation in Pakistan in line with international practices.