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Journal of Molecular Immunology
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Non classical MHC class I molecules

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Non classical MHC class I molecules

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Non classical MHC class I molecules

Nonclassical molecules (MHC class IB) exhibit limited polymorphism and expression than MHC Ia. It may be recognised by specific subsets of T-cell receptors or by innate immune receptors. Owing to their recognition by a more restricted set of receptors, MHC芒鈧怚b are able to elicit a rapid response from immune cells and are, therefore, regarded as part of the innate immune system. Some MHC芒鈧怚b act as antigen presenting structures, whereas others are recognised as direct ligands for immune receptors.

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Non classical MHC class I molecules

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